GW-1516 SARMs has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound such as AICAR.The mechanism by which PPARδ agonists increase HDL seems to be a consequence of increased expression of ABCA1, the cholesterol transporter.
GW1516 SARMS (also known as GW-501,516, GW1516, GSK-516 and Endurobol) is a PPAR receptor. It activates the same pathways activated through exercise, including PPAR and AMP-activated protein kinase. It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW-1516 SARMS has a half-life of 16 hours.
GW-1516 SARMS (Cardarine) was primarily developed to treat obesity, diabetes, lipid strain, and heart health problems. As a matter of fact, those who run blood work will notice that cardarine will magically aid with lipid strain, and their cholesterol levels will improve substantially.
Endurance athletes may increase exercise endurance. As a result, they will have a greater ability to reach higher RPM’s during their runs without hitting the maximum heart rate. Regarding the bodybuilders, cardarine can benefit them in two ways:
1. Its ability to burn fat
2. Its ability to help the athlete have harder and longer workouts, without getting winded.
In terms of obesity, cardarine reverses metabolic abnormalities in obese and pre-diabetic men by stimulating fatty acid oxidation. That is, it burns fat by increasing glucose uptake in skeletal muscle tissue, which changes the body’s metabolism to burn fat for energy instead of muscle or carbs. Incredibly, it does all this without dropping blood sugar levels like diabetic drugs do. Interestingly, when mice were given a high fat diet, they still lost fat, which proves that cardarine prevents obesity.
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